产品货号：
Z13373
中文名称：
Claudin 16/CLDN16抗体
英文名称：
Anti-Claudin 16/CLDN16 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Claudin 16/CLDN16 Antibody |
| 指标别名 | claudin 16,CLDN16,HOMG3,Paracellin 1,PCLN 1,PCLN1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | CLDN16 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human Claudin CLDN16/Claudin-16 (KSYSAPRTETAKMYAVDTRV). |
| 实际分子量 | 34KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Claudin-16 is a protein that in humans is encoded by the CLDN16 gene.Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets,forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet,with complementary grooves in the inwardly facing extracytoplasmic leaflet.The protein encoded by this gene,a member of the claudin family,is an integral membrane protein and a component of tight junction strands.It is found primarily in the kidneys,specifically in the thick ascending limb of Henle,where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions.Defects in this gene are a cause of primary hypomagnesemia,which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria,resulting in nephrocalcinosis and renal failure.This gene and the CLDN1 gene are clustered on chromosome 3q28. |
| Uniprot ID | Q9Y5I7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | claudin 16 |
| 蛋白名全称 | Claudin-16 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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